The C allele= an increase in VEGFA levels and expression [R].
The C (minor) allele is associated with:
- Increased risk of AMD (age related macular degeneration) [R].
- a 6.25-fold increased risk of Polypoidal Choroidal Vasculopathy (CC vs TT) while the CT group had a 1.82-fold increased risk (Koreans). [R]
- Lower likelihood of Diabetic retinopathy (DR) ,which accounts for 8% of legal blindness in the United States [R].
An increased survival rate in children after surgery for Congenital Heart Disease (CHD) [R]
An increased overall survival rate in children with severe CHD [R].
A 5-fold increased risk of developing Age-related Macular Degeneration (AMD) [R]
The “T” (major) allele is associated with:
This SNP is associated with (unknown which alleles):