The T (minor) allele is associated with:

  • Lower insulin with each T allele and higher fasting glucose due to a lack of insulin secretion from GLP-1 and GLP.
  • Lower glucagon although it increases the risk of diabetes.
  • A 1.4 fold increased risk for T2DB from one T allele and a 2.15 fold increased risk for colon cancer.

rs7903146

Parent Gene: TCF7L2

Importance: 5
Less common allele: None = None
More common allele: C = None
My Genotype: Log In
Risk Allele: T, A, T, T, T, T, T, T, T, A, C, T, T, T, T, T, T, T, T, T, T, T, C, C, C, T, T, T, T, T, T, T

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Type Ii Diabetes Mellitus

rs7903146 is associated with Type Ii Diabetes Mellitus (R) . It is reported to increased association with Type 2 diabetes. No specific risk allele was identified in the study.

Disease/Trait: Type Ii Diabetes Mellitus

The A allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Type Ii Diabetes Mellitus

rs7903146 is associated with Type Ii Diabetes Mellitus (R) . It is reported to increased association with Type 2 diabetes (obese). No specific risk allele was identified in the study.

Disease/Trait: Type Ii Diabetes Mellitus

rs7903146 is associated with Type Ii Diabetes Mellitus (R) . It is reported to increased association with Type 2 diabetes (non-obese). No specific risk allele was identified in the study.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Autoantibody Measurement

The T allele of rs7903146 is reported to be associated with Autoantibody Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes and other traits.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes and other traits.

Disease/Trait: Insulin Measurement

The T allele of rs7903146 is reported to be associated with Insulin Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Proinsulin levels.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Metabolic Syndrome

The A allele of rs7903146 is reported to be associated with Metabolic Syndrome (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Metabolic syndrome (T2D).

Disease/Trait: Type Ii Diabetes Mellitus

The A allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Metabolic syndrome (T2D).

Disease/Trait: A1c Measurement

The C allele of rs7903146 is reported to be associated with A1c Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Glycated hemoglobin levels.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (Lean).

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (Obese).

Disease/Trait: Fasting Blood Insulin Measurement

rs7903146 is associated with Fasting Blood Insulin Measurement (R) . It is reported to association with Fasting insulin-related traits (interaction with BMI). No specific risk allele was identified in the study.

Disease/Trait: Body Mass Index

rs7903146 is associated with Body Mass Index (R) . It is reported to association with Fasting insulin-related traits (interaction with BMI). No specific risk allele was identified in the study.

Disease/Trait: Fasting Blood Glucose Measurement

rs7903146 is associated with Fasting Blood Glucose Measurement (R) . It is reported to association with Fasting glucose-related traits (interaction with BMI). No specific risk allele was identified in the study.

Disease/Trait: Body Mass Index

rs7903146 is associated with Body Mass Index (R) . It is reported to association with Fasting glucose-related traits (interaction with BMI). No specific risk allele was identified in the study.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (Punjabi Sikhs).

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (All Punjabi).

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (South Asians).

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (South Asians, East Asians).

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (South Asian, East Asian, Europeans).

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (Indo-European South Asians).

Disease/Trait: Body Mass Index

The C allele of rs7903146 is reported to be associated with Body Mass Index (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Body mass index.

Disease/Trait: Body Mass Index

The C allele of rs7903146 is reported to be associated with Body Mass Index (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Body mass index (EA, men).

Disease/Trait: Body Mass Index

The C allele of rs7903146 is reported to be associated with Body Mass Index (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Body mass index (EA).

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes (AA).

Disease/Trait: Type Ii Diabetes Mellitus

The T allele of rs7903146 is reported to be associated with Type Ii Diabetes Mellitus (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Type 2 diabetes.

Disease/Trait: Glucose Measurement

rs7903146 is associated with Glucose Measurement (R) . It is reported to association with Clinical laboratory measurements (glucose levels). No specific risk allele was identified in the study.

Disease/Trait: Clinical Laboratory Measurement

rs7903146 is associated with Clinical Laboratory Measurement . It is reported to association with Clinical laboratory measurements (glucose levels). No specific risk allele was identified in the study.

Disease/Trait: Waist Circumference

The T allele of rs7903146 is reported to be associated with Waist Circumference (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Waist circumference (EA, men).

Disease/Trait: Waist Circumference

The T allele of rs7903146 is reported to be associated with Waist Circumference (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Waist circumference (EA).

Disease/Trait: Hip Circumference

The T allele of rs7903146 is reported to be associated with Hip Circumference (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Hip circumference (EA).

Disease/Trait: Hip Circumference

The T allele of rs7903146 is reported to be associated with Hip Circumference (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Hip circumference (EA,women).

Disease/Trait: Hip Circumference

The T allele of rs7903146 is reported to be associated with Hip Circumference (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Hip circumference (EA, men).