Mechanism:

  • Increased production of the catalase gene (T) [R]

  • Decreased transcription of the catalase gene (C) [R]

The Minor "T" allele is associated with:

  • Higher blood lead concentrations [R]

  • Increased oxidative stress [R]

  • Decreased femur density in males [R]

  • More efficient body glucose disposal in females [R]

The Major "C" allele is associated with:

  • Decreased blood lead concentrations [R]

  • Decreased oxidative stress [R]

  • Increased femur density in males [R]

  • Less efficient body glucose disposal in females [R]

This SNP is associated with (unknown  which alleles):

  • Increased vitiligo (skin blotching) susceptibility [R]

  • Decreased pulmonary function in elderly members of the Korean population [R]

  • Increased susceptibility to cardiac problems after exposure to air pollution [R]

  • Increased susceptibility to microcytic anemia [R]

rs769217

Parent Gene: CAT

Importance: 3
Less common allele: T = 26%
More common allele: C = 74%
My Genotype: Log In