Mechanisms:

  • this gene variation interact with other genes causing low enzymatic activity associated with high pain sensitivity [R].

The Minor "T" allele is associated with:

  • high pain sensitivity (TT) [R].

The Major "G" allele is associated with:

  • thinking and disciplinary problems in children with attention deficit hyperactivity disorder (GG) [R].

rs6267

Parent Gene: COMT

Importance: 2
Less common allele: T = 1%
More common allele: G = 99%
My Genotype: Log In