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The Minor "A" allele is associated with: 

  • AA may have a genetic immunity to infection by the Norwalk norovirus, a cause of gastroenteritis (R).
  • "AA" leads to the absence of ABH blood groups in body fluids (R).
  • AA increases the risk of developing Celiacs by 1.28X (P=0.0074) (R).
  • The A allele showed some protection from Ulcerative Colitis and Crohn's Disease (P=0.035, OR: 0.84) (R).

The Major "G" allele is associated with:

  • Possible increased risk of developing Irritable Bowel Syndrome (IBD) in the Finnish population (R).
  • Higher levels of Bifidobacteria in the body (R).


Parent Gene: FUT2

Importance: 3
Less common allele: A = 32%
More common allele: G = 68%
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Risk Allele: A, A