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The Minor "G" allele is associated with:

  • Women homozygous for the allele had higher B(12) levels in the blood (R). This is thought to be caused by increased B(12) absorption.

The Major "A" allele is associated with:

  • The A allele is more likely to contract H pylori (R) The H-antigen synthesized by FUT2 allows H. pylori to take hold in the gut (R).
  • Absorption of B12 requires the secretion of intrinsic factor (IF) from the gastric cells, binding of IF to vitamin B12 and a functional gastrointestinal absorption system.
  • Possible malabsorption of vitamin B12 (R).

rs492602

Parent Gene: FUT2

Importance: 5
Less common allele: G = 32%
More common allele: A = 68%
My Genotype: Log In
Risk Allele: G, C, G, G, A

Disease/Trait: Psoriasis

The G allele of rs492602 is reported to be associated with Psoriasis (R). Your genotype was not identified for this SNP so we are unable to comment on your association with Psoriasis.

Disease/Trait: Vitamin B12 Measurement

The C allele of rs492602 is reported to be associated with Vitamin B12 Measurement (R). Your genotype was not identified for this SNP so we are unable to comment on your association with Vitamin B levels in ischemic stroke (Vitamin B12).

Disease/Trait: Total Cholesterol Measurement

The G allele of rs492602 is reported to be associated with Total Cholesterol Measurement (R). Your genotype was not identified for this SNP so we are unable to comment on your association with Cholesterol, total.

Disease/Trait: Total Cholesterol Measurement

The G allele of rs492602 is reported to be associated with Total Cholesterol Measurement (R). Your genotype was not identified for this SNP so we are unable to comment on your association with Cholesterol, total.

Disease/Trait: Vitamin B12 Measurement

The A allele of rs492602 is reported to be associated with Vitamin B12 Measurement (R). Your genotype was not identified for this SNP so we are unable to comment on your association with Vitamin B12 levels.