The Minor "G" allele is associated with:

  • Women homozygous for the allele had higher B(12) levels in the blood (R). This is thought to be caused by increased B(12) absorption.

The Major "A" allele is associated with:

  • The A allele is more likely to contract H pylori (R) The H-antigen synthesized by FUT2 allows H. pylori to take hold in the gut (R).
  • Absorption of B12 requires the secretion of intrinsic factor (IF) from the gastric cells, binding of IF to vitamin B12 and a functional gastrointestinal absorption system.
  • Possible malabsorption of vitamin B12 (R).

rs492602

Parent Gene: FUT2

Importance: 5
Less common allele: G = 32%
More common allele: A = 68%
My Genotype: Log In
Risk Allele: G, C, G, G, A

Disease/Trait: Psoriasis

The G allele of rs492602 is reported to be associated with Psoriasis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Psoriasis.

Disease/Trait: Vitamin B12 Measurement

The C allele of rs492602 is reported to be associated with Vitamin B12 Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Vitamin B levels in ischemic stroke (Vitamin B12).

Disease/Trait: Total Cholesterol Measurement

The G allele of rs492602 is reported to be associated with Total Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cholesterol, total.

Disease/Trait: Total Cholesterol Measurement

The G allele of rs492602 is reported to be associated with Total Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Cholesterol, total.

Disease/Trait: Vitamin B12 Measurement

The A allele of rs492602 is reported to be associated with Vitamin B12 Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Vitamin B12 levels.