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The “A” minor allele is associated with:

  • Protection against short sightedness. [R]

  • Colon cancer [R]

  • Breast cancer risk among Hispanic and Non-hispanic white women [R].

  • Difficult pregnancy (preeclamsia) [R].

The “C” major allele is associated with:

  • Higher number of fat clots in arteries in Chinese males. [R]

rs4803455

Parent Gene: TGFB1

Importance: 3
Less common allele: A = 48%
More common allele: C = 52%
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Risk Allele: