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rs45475795

Parent Gene: IL2, IL21
Importance: 3
Minor Allele: G = 3%
Major Allele: A = 97%
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Risk Allele: G

Disease/Trait: Rheumatoid Arthritis

The G allele of rs45475795 is reported to be associated with Rheumatoid Arthritis(R). Your genotype was not identified for this SNP so we are unable to comment on your association with Rheumatoid arthritis (EA).

Reported risk allele frequency: 7.00%
Reported genes: IL2 , IL21
Odds ratio: 1.14
Risk Allele: G (P=4.00*10-6)
Context: intergenic_variant
Study title: Genetics of rheumatoid arthritis contributes to biology and drug discovery. (R)
Initial sample size: up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls
Replication sample size: up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls
Journal: Nature (R)
Year published: Dec. 25, 2013
Strength of evidence: Strong