The SNP is associated with the following:

  • Cardiovascular disease risk factors (P=9.00*10-19) (R)
  • Carotid intima media thickness (P=2.00*10-8) (R)
  • Apolipoprotein Levels (P=2.00*10-14) (R)
  • Lipoprotein-associated phospholipase A2 activity and mass (P=1.00*10-56) (R)
  • Blood metabolite ratios (P=5.00*10-23) (R)
  • Response to statins (LDL cholesterol change) (P=9.00*10-29) (R).

Incomplete

rs445925

Parent Gene: APOC1, APOE

Importance: 5
Less common allele: A = 15%
More common allele: G = 85%
My Genotype: Log In
Risk Allele: A, G, G, G, T, A, A, A, A, A, A

Disease/Trait: Atherosclerosis

The A allele of rs445925 is reported to be associated with Atherosclerosis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Carotid intima media thickness (cIMT).

Disease/Trait: Atherosclerosis

The G allele of rs445925 is reported to be associated with Atherosclerosis (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Carotid intima media thickness (plaque).

Disease/Trait: Coronary Artery Calcification

rs445925 is associated with Coronary Artery Calcification (R) . It is reported to association with Metabolite levels. No specific risk allele was identified in the study.

Disease/Trait: Lipoprotein Measurement

The G allele of rs445925 is reported to be associated with Lipoprotein Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Apolipoprotein Levels (APOB).

Disease/Trait: Lipoprotein Measurement

The G allele of rs445925 is reported to be associated with Lipoprotein Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Apolipoprotein Levels (APOE).

Disease/Trait: Lipoprotein-Associated Phospholipase A(2) Measurement

The T allele of rs445925 is reported to be associated with Lipoprotein-associated Phospholipase A(2) Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Lipoprotein-associated phospholipase A2 activity and mass (activity).

Disease/Trait: Low Density Lipoprotein Cholesterol Measurement

The A allele of rs445925 is reported to be associated with Low Density Lipoprotein Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Response to statins (LDL cholesterol change).

Disease/Trait: Response To Statin

The A allele of rs445925 is reported to be associated with Response To Statin (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Response to statins (LDL cholesterol change).

Disease/Trait: Clinical Ideal Cardiovascular Health

The A allele of rs445925 is reported to be associated with Clinical Ideal Cardiovascular Health . Your genotype was not identified for this SNP so we are unable to comment on your association with Ideal cardiovascular health (clinical).

Disease/Trait: Blood Metabolite Measurement

The A allele of rs445925 is reported to be associated with Blood Metabolite Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Blood metabolite ratios (X-11820/cholesterol).

Disease/Trait: Ldl Cholesterol Change Measurement

The A allele of rs445925 is reported to be associated with Ldl Cholesterol Change Measurement . Your genotype was not identified for this SNP so we are unable to comment on your association with LDL cholesterol levels.

Disease/Trait: Low Density Lipoprotein Cholesterol Measurement

The A allele of rs445925 is reported to be associated with Low Density Lipoprotein Cholesterol Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with LDL cholesterol levels (BMI unadjusted).