Mechanism:

  • Glycogen Synthase Kinase 3 (GSK3B) is responsible for phosphorylation, protein complexes, localization, and substrate phosphorylation. (R)

The Minor “G” Allele is Associated With:

  • strongly associated with schizophrenia (R)
  • lowered risk of tardive dyskinesia (TD) and lower Abnormal Involuntary Movement Scale (R)
  • Recent studies suggest increased lung cancer susceptibility (R)

 

rs4072520

Parent Gene: GSK3B

Importance: 2
Less common allele: A = 28%
More common allele: None = None
My Genotype: Log In