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The T (minor) allele is associated with:

  • Increased risk of developing intrahepatic cholestasis of pregnancy (ICP) [R].
  • The risk allele is (T), and the odds ratio for homozygous (TT) mothers is 4.44 (CI: 1.83 - 10.78), and for heterozygous mothers 1.65 (CI: 0.76 - 3.64), compared to (CC) mothers [R].


Parent Gene: ABCC2
Importance: 2
Minor Allele: None = None
Major Allele: = None
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