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[PMID 19551864] Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease

[PMID 17063263] Genetic variation in IGF1, IGF-1R, IGFALS, and IGFBP3 in breast cancer survival among Chinese women: a report from the Shanghai Breast Cancer Study.

[PMID 17300730] Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study.

[PMID 17566087] Genetic determinants of circulating insulin-like growth factor (IGF)-I, IGF binding protein (BP)-1, and IGFBP-3 levels in a multiethnic population.

[PMID 18163429] Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study.

[PMID 18596909] IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).

[PMID 18772892] Can genes for mammographic density inform cancer aetiology?

[PMID 19124510] Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.

[PMID 19240240] IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women.

[PMID 19603096] An analysis of growth, differentiation and apoptosis genes with risk of renal cancer.

[PMID 19938081] Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.

[PMID 20144192] Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy.

[PMID 22354904] Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study.


Parent Gene: IGFBP3
Importance: 1
Minor Allele: A = 42%
Major Allele: G = 58%
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