Mechanism:

  • Lower levels of FOX03a protein (T)
  • Normal levels of FOX03a protein (G)

The Major "G" allele is associated with:

  • 1.5x~2.7x more likely to live to 100 (GG).
  • Enhanced insulin sensitivity in a small twin cohort (R).

GT is associated with:

  • Slightly increased lifespan.

 

rs2802292

Parent Gene: FOXO3A

Importance: 5
Less common allele: T = 47%
More common allele: G = 53%
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