The "T" (minor) allele is associated with:

  • TT= 2X increase risk sudden cardiac death.
  • TT= increased artery narrowing.
  • TT= increased atherosclerotic lesions.
  • Apigenin inhibits
  • Transcription factor encodes for lipid accumulation, inflammation, and thrombotic complications of the coronary plaque

rs2516839

Parent Gene: USF1

Importance: 3
Less common allele: T = 40%
More common allele: C = 60%
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