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rs2069705 was associated with systemic lupus erythematosus (SLE) susceptibility (OR 2.27, p=0.0024) [R]. 

rs2069705 (no reported alleles) was significantly associated with breast cancer [R]. 

The ''GA/AA'' genotypes were significantly related to an elevated risk of breast cancer (OR=1.32) among the women with <1 fever per year and to a reduced risk of breast cancer (OR=0.63) among women with ≥1 fever per year compared to the ''GG'' genotype [R]. 

Significantly higher response rate to Imatinib therapy in Chronic Myeloid Leukemia (CML) was noted for the ''GG'' genotype both in overall patients and in chronic phase (CP) patients only compared with those with ''GA'' or ''AA'' genotype [R]. 

Among women with the ''GG'' genotype, Epstein-Barr virus nuclear antigen-1 (EBNA-1) IgA seropositivity significantly increased the risk of breast cancer (BC) compared to EBNA-1 IgA seronegativity (OR, 5.14) [R]. 

A/G polymorphism was strongly associated with severe malaria in Indian populations [R].

''G'' allele influences the risk of invasive aspergillosis (IA) [R].

 

rs2069705

Parent Gene: IFNG

Importance: 2
Less common allele: G = 48%
More common allele: A = 52%
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