rs174583 is located in the FADS2 gene. In one study, it was assigned a 10% posterior probability of association with statin-induced change in triglyceride (pā€Š=ā€Š0.01).

It has also been identified to be strongly associated with baseline triglycerides and HDLC (High-density lipoprotein cholesterol) [R].

Women with the minor allele homozygotes ''TT'' had a lower ARA (arachidonic acid) but higher LA (linolenic acid) in plasma phospholipids and EPG (erythrocyte ethanolamine phosphoglyceride) and decreased (n-6) and (n-3) fatty acid product:precursor ratios at 16 and 36 wk of gestation [R].

 

rs174583

Parent Gene: FADS2

Importance: 2
Less common allele: T = 37%
More common allele: C = 63%
My Genotype: Log In
Risk Allele: T, T, T

Disease/Trait: Trans Fatty Acid Measurement

The T allele of rs174583 is reported to be associated with Trans Fatty Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Trans fatty acid levels (Cis/trans-18:2, EA).

Disease/Trait: Cis/Trans-18:2 Fatty Acid Measurement

The T allele of rs174583 is reported to be associated with Cis/trans-18:2 Fatty Acid Measurement (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Trans fatty acid levels (Cis/trans-18:2, EA).

Disease/Trait: Qt Interval

The T allele of rs174583 is reported to be associated with Qt Interval (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with QT interval.

Disease/Trait: Response To Statin

The T allele of rs174583 is reported to be associated with Response To Statin (R) . Your genotype was not identified for this SNP so we are unable to comment on your association with Response to statin therapy (Triglyceride, sum).