Summary of UGT2B7

UGT2B7 (UDP-Glucuronosyltransferase-2B7) is a phase II enzyme found in the liver, kidneys, GI tract and brain. UGT2B7 has unique specificity for estrogen metabolites 3,4-catechol estrogens and estriol.


The Function of UGT2B7

Its unique specificity for 3,4-catechol estrogens and estriol suggests it may play an important role in regulating the level and activity of these potent and active estrogen metabolites. Is also active with androsterone, hyodeoxycholic acid and tetrachlorocatechol (in vitro).

Protein names

Recommended name:

UDP-glucuronosyltransferase 2B7

Alternative name(s):

UDPGT 2B7
3,4-catechol estrogen-specific UDPGT
UDP-glucuronosyltransferase 2B9
UDPGT 2B9
UDPGTh-2

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Top Gene-Substance Interactions

UGT2B7 Interacts with These Diseases

Substances That Increase UGT2B7

Substances That Decrease UGT2B7

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical