Summary of UCP3

UCP encodes mitochondrial transporter proteins that help release energy is in the form of heat through ATP synthesis (R). 

It is associated with higher risk for obesity (R). 

The Function of UCP3

UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.

Protein names

Recommended name:

Mitochondrial uncoupling protein 3

Short name:


Alternative name(s):

Solute carrier family 25 member 9

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Top Gene-Substance Interactions

UCP3 Interacts with These Diseases


Substances That Increase UCP3

Substances That Decrease UCP3

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity