Function

May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.

Protein names

Recommended name:

Tomoregulin-2

Short name:

TR-2

Alternative name(s):

Hyperplastic polyposis protein 1
Transmembrane protein with EGF-like and two follistatin-like domains

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Top Gene-Substance Interactions

TMEFF2 Interacts with These Diseases

Substances That Increase TMEFF2

Substances That Decrease TMEFF2

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical