Summary of TCN1
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
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Protein names
Recommended name:
Transcobalamin-1Short name:
HCAlternative name(s):
TC-1Haptocorrin
Protein R
Transcobalamin I
TC I
TCI
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- RS34324219 (TCN1) ??
- RS526934 (TCN1) ??
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Top Gene-Substance Interactions
Substances That Increase TCN1
| Substances | Interaction | Organism | Category |
Substances That Decrease TCN1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.
Gene Pathways:
Molecular Function:
Biological Processes:
Drug Bank:
- Cyanocobalamin
- Hydroxocobalamin