Summary of SOD1

The SOD1 gene provides instructions for making an enzyme called superoxide dismutase, which is abundant in cells throughout the body. This enzyme attaches (binds) to molecules of copper and zinc to break down toxic, charged oxygen molecules called superoxide radicals. The molecules are byproducts of normal cell processes, and they must be broken down regularly to avoid damaging cells.

Defects in the SOD1 gene can cause ALS.

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Protein names

Recommended name:

Superoxide dismutase [Cu-Zn]

Alternative name(s):

Superoxide dismutase 1

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Top Gene-Substance Interactions

SOD1 Interacts with These Diseases


Substances That Increase SOD1

Substances That Decrease SOD1

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity