The SOD1 gene provides instructions for making an enzyme called superoxide dismutase, which is abundant in cells throughout the body. This enzyme attaches (binds) to molecules of copper and zinc to break down toxic, charged oxygen molecules called superoxide radicals. The molecules are byproducts of normal cell processes, and they must be broken down regularly to avoid damaging cells.

Defects in the SOD1 gene can cause ALS.

It's better to have this gene increased most of the time.

Protein names

Recommended name:

Superoxide dismutase [Cu-Zn]

Alternative name(s):

Superoxide dismutase 1

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