Summary of SLC2A2

The gene codes for a protein, solute carrier family 2 member 2. Mutations are linked to diseases including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM) [R].


The Function of SLC2A2

Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.

Protein names

Recommended name:

Solute carrier family 2, facilitated glucose transporter member 2

Short name:

GLUT-2

Alternative name(s):

Glucose transporter type 2, liver

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Top Gene-Substance Interactions

SLC2A2 Interacts with These Diseases

Substances That Increase SLC2A2

Substances That Decrease SLC2A2

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical