SLC23A1 | SelfDecode | Genome Analysis

Summary of SLC23A1

The gene codes for a protein, solute carrier family 23 member 1. It is one of the two transporters that aids with the absorption of vitamin C into the body and the distribution of it to the organs requires two sodium-dependent vitamin C transporters [R].

The Function of SLC23A1

Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.

Protein names

Recommended name:

Solute carrier family 23 member 1

Alternative name(s):

Na(+
Sodium-dependent vitamin C transporter 1
hSVCT1
Yolk sac permease-like molecule 3

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RS10063949 (SLC23A1) ??
RS11950646 (SLC23A1) ??
RS33972313 (SLC23A1) ??

Top Gene-Substance Interactions

SLC23A1 Interacts with These Diseases

Disease	Score

Substances That Increase SLC23A1

Category:

Substances	Interaction	Organism	Category

Substances That Decrease SLC23A1

Category:

Substances	Interaction	Organism	Category

Conditions with Increased Gene Activity

Experimental Variables:

Condition	Change (log₂fold)	Comparison	Species	Experimental variables	Experiment name

Conditions with Decreased Gene Activity

Experimental Variables:

Condition	Change (log₂fold)	Comparison	Species	Experimental variables	Experiment name

Technical

The following transcription factors affect gene expression (R):

Tissue specificity:

Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.

Gene Pathways:

Molecular Function:

Biological Processes:

Drug Bank:

Vitamin C

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| SLC23A2| solute carrier family 23 (nucleobase transporters), member 2| A306_14690| AS27_09540| D18Ucla2| D623_10027804| H920_19251| hSVCT1| I79_014960| M91_15312| M959_06941| Marginal zone B- and B1-cell-specific protein| MDA_GLEAN10012462| N300_15925| N302_13646| N303_10658| N307_06391| N309_01157| Na(+)/L-ascorbic acid transporter 1| sodium-coupled ascorbic acid transporter 1| sodium-dependent vitamin C transporter 1| sodium-dependent vitamin C transporter-1| solute carrier family 23 (ascorbic acid transporter), member 1| solute carrier family 23 , member 1| solute carrier family 23 member 1-like protein| solute carrier family 23 (nucleobase transporters), member 1| SVCT1| TREES_T100019639| UY3_06473| Y1Q_030780| Y956_14157| yolk sac permease-like molecule 3| YSPL3| slc23a1

SLC23A1 (Solute carrier family 23 member 1)