The Function of SLC1A3

Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

Protein names

Recommended name:

Excitatory amino acid transporter 1

Short name:


Alternative name(s):

Sodium-dependent glutamate/aspartate transporter 1
Solute carrier family 1 member 3

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Top Gene-Substance Interactions

SLC1A3 Interacts with These Diseases

Substances That Increase SLC1A3

Substances That Decrease SLC1A3

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity