Summary of SKAP2

The gene codes for a protein, src kinase associated phosphoprotein 2. It plays a vital role in the Src signaling pathway, and in regulating proper activation of the immune system [R].

The Function of SKAP2

May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.

Protein names

Recommended name:

Src kinase-associated phosphoprotein 2

Short name:


Alternative name(s):

Pyk2/RAFTK-associated protein
Retinoic acid-induced protein 70
SKAP55 homolog
Src family-associated phosphoprotein 2
Src kinase-associated phosphoprotein 55-related protein
Src-associated adapter protein with PH and SH3 domains

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Top Gene-Substance Interactions

SKAP2 Interacts with These Diseases

Substances That Increase SKAP2

Substances That Decrease SKAP2

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity