The Function of SERPINB5

Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Protein names

Recommended name:

Serpin B5

Short name:

PI-5

Alternative name(s):

Maspin
Peptidase inhibitor 5

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Top Gene-Substance Interactions

SERPINB5 Interacts with These Diseases

Substances That Increase SERPINB5

Substances That Decrease SERPINB5

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical