Summary

The gene codes for a protein, serpin family A member 3. Variations are linked to Alzheimer's disease, and deficiency may cause liver disease. Mutations are associated with Parkinson disease and chronic obstructive pulmonary disease [R].


Function

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.

Get a Grip on Your Health. Use SelfDecode to Interpret your Genome Today! GET INSTANT ACCESS

Top Gene-Substance Interactions

Gene Interacts with Diseases

All Ways to Increase Gene

All Ways to Decrease Gene

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical