Summary of SERPINA1

The SERPINA1 gene encodes a protein called alpha-1 antitrypsin, which is a serine protease inhibitor. It helps control chemical reactions in the body (R). 


Function

Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).

Protein names

Recommended name:

Alpha-1-antitrypsin

Short name:

SPAAT

Alternative name(s):

Alpha-1 protease inhibitor
Alpha-1-antiproteinase
Serpin A1

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Top Gene-Substance Interactions

SERPINA1 Interacts with These Diseases

Substances That Increase SERPINA1

Substances That Decrease SERPINA1

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical