Summary of PGR

Progesterone receptor (PGR) gene is associated with action of the hormone progesterone, which is involved in egg cells development in humans and other mammals [R], as well as in maintaining healthy pregnancy [R].

PR-A inhibits most hormone receptors, whereas PR-B is an activator of gene activity [R].


The Function of PGR

Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

Protein names

Recommended name:

Progesterone receptor

Short name:

PR

Alternative name(s):

Nuclear receptor subfamily 3 group C member 3

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Top Gene-Substance Interactions

PGR Interacts with These Diseases

Substances That Increase PGR

Substances That Decrease PGR

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical