The Function of PDE4B

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.

Protein names

Recommended name:

cAMP-specific 3',5'-cyclic phosphodiesterase 4B

Short name:


Alternative name(s):


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Top Gene-Substance Interactions

PDE4B Interacts with These Diseases

Substances That Increase PDE4B

Substances That Decrease PDE4B

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity