The Function of PCDH8

Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis.

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Top Gene-Substance Interactions

PCDH8 Interacts with These Diseases

Substances That Increase PCDH8

Substances That Decrease PCDH8

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity