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  1. Home
  2. Genes
  3. MUT

MUT (Methylmalonyl-CoA mutase)

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The Function of MUT

Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species.

Protein names

Recommended name:

Methylmalonyl-CoA mutase, mitochondrial

Short name:

MCM

Alternative name(s):

Methylmalonyl-CoA isomerase

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MUT SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS9369898 (MUT) ??
  2. RS9473555 (MUT) ??

Top Gene-Substance Interactions

MUT Interacts with These Diseases

Disease Score

Substances That Increase MUT

Substances Interaction Organism Category

Substances That Decrease MUT

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • STAT1
  • STAT1alpha
  • STAT1beta
  • C/EBPbeta
  • PPAR-alpha
  • c-Myc

Gene Pathways:

  • Propanoate metabolism
  • Valine, leucine and isoleucine degradation
  • Metabolism
  • Metabolic pathways
  • Glyoxylate and dicarboxylate metabolism
  • Disease

Molecular Function:

  • Methylmalonyl-Coa Mutase Activity
  • Cobalamin Binding
  • Metal Ion Binding
  • Modified Amino Acid Binding

Biological Processes:

  • Cobalamin Metabolic Process
  • Post-Embryonic Development
  • Short-Chain Fatty Acid Catabolic Process
  • Homocysteine Metabolic Process

Drug Bank:

  • Cyanocobalamin
  • Hydroxocobalamin
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| MCM| Anapl_01262| AS27_12649| AS28_01589| CB1_001402128| D623_10026047| GW7_03041| H920_08218| I79_019024| M959_15274| methylmalonyl-CoA isomerase| methylmalonyl CoA mutase| Methylmalonyl-CoA mutase, mitochondrial| methylmalonyl-CoA mutase mitochondrial-like protein| methylmalonyl-CoA mutase, mitochondrial-like protein| methylmalonyl Coenzyme A mutase| methylmalonyl-Coenzyme A mutase| mutant methylmalonyl CoA mutase| N300_02183| N301_07782| N302_01968| N303_06847| N305_01425| N306_06348| N307_02955| N308_14991| N309_13292| N310_04824| N311_11142| N312_11860| N320_08710| N321_11193| N322_01288| N324_04493| N325_12427| N326_11636| N328_05654| N329_05231| N330_01837| N331_02104| N332_02259| N333_12551| N334_05254| N335_09587| N336_09624| N339_05089| N340_09256| N341_12852| PAL_GLEAN10025342| PANDA_003473| TREES_T100007637| truncated methylmalonyl CoA mutase| UY3_08831| Y1Q_017398| Y956_03731| Z169_05207| mut
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