Summary of MSR1

The gene codes for a protein, macrophage scavenger receptor 1. It is implicated in atherosclerosis, Alzheimer's disease, and host defense [R].


The Function of MSR1

Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.

Protein names

Recommended name:

Macrophage scavenger receptor types I and II

Alternative name(s):

Macrophage acetylated LDL receptor I and II
Scavenger receptor class A member 1
CD antigen CD204

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Top Gene-Substance Interactions

MSR1 Interacts with These Diseases

Substances That Increase MSR1

Substances That Decrease MSR1

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical