The Function of MS4A3
Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP).
Protein names
Recommended name:
Membrane-spanning 4-domains subfamily A member 3Alternative name(s):
CD20 antigen-like proteinHematopoietic-specific transmembrane protein 4
HTm4
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- RS2298585 (MS4A3) ??
- RS474951 (MS4A3) ??
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Top Gene-Substance Interactions
MS4A3 Interacts with These Diseases
Disease | Score |
Substances That Increase MS4A3
Substances | Interaction | Organism | Category |
Substances That Decrease MS4A3
Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed specifically in hematopoietic cells and tissues.