Summary of MC3R

The gene codes for a protein, melanocortin 3 receptor. Mutations are linked to a higher chance of obesity in humans [R].

The Function of MC3R

Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.

Protein names

Recommended name:

Melanocortin receptor 3

Short name:


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Top Gene-Substance Interactions

MC3R Interacts with These Diseases

Substances That Increase MC3R

Substances That Decrease MC3R

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity