• Navigation
  • Personalized Genetics Blog
  • Wellness Reports
  • About
  • Login
  • Analyze My Genes
  1. Home
  2. Genes
  3. LIFR

LIFR (Leukemia inhibitory factor receptor alpha)

Loading...

The Function of LIFR

Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Leukemia inhibitory factor receptor

Short name:

LIF-R

Alternative name(s):

LIF receptor
CD antigen CD118

Top Gene-Substance Interactions

LIFR Interacts with These Diseases

Disease Score

Substances That Increase LIFR

Substances Interaction Organism Category

Substances That Decrease LIFR

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • STAT3
  • Sox9
  • GR
  • GR-alpha
  • GR-beta
  • PPAR-gamma1
  • PPAR-gamma2

Gene Pathways:

  • Jak-STAT signaling pathway
  • Cytokine-cytokine receptor interaction

Molecular Function:

  • Leukemia Inhibitory Factor Receptor Activity
  • Ciliary Neurotrophic Factor Receptor Binding
  • Growth Factor Binding

Biological Processes:

  • Cell Surface Receptor Signaling Pathway
  • Positive Regulation Of Cell Proliferation
  • Negative Regulation Of Muscle Cell Apoptotic Process
  • Response To Organic Cyclic Compound
  • Cytokine-Mediated Signaling Pathway
  • Response To Cytokine
  • Oncostatin-M-Mediated Signaling Pathway
  • Neuron Projection Morphogenesis
  • Leukemia Inhibitory Factor Signaling Pathway
  • Ciliary Neurotrophic Factor-Mediated Signaling Pathway
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| SWS| CD118| Anapl_16164| AS27_01112| AS28_11262| CD118 antigen| cytokine receptor-beta| D623_10029249| D-factor/LIF receptor| GW7_20811| I79_009841| leukemia inhibitor factor receptor alpha-chain| leukemia inhibitory factor receptor| leukemia inhibitory factor receptor alpha chain| LIF| LIF-R| LIF receptor| M959_07441| MDA_GLEAN10023485| N300_07415| N301_10871| N303_04224| N306_15474| N307_06331| N308_09887| N309_03072| N310_04010| N311_09285| N320_07756| N324_05329| N325_11075| N326_09262| N327_08328| N328_09370| N329_11912| N330_13309| N331_03447| N332_14054| N333_03226| N334_02742| N335_06431| N336_01843| N339_06671| N340_02293| N341_04111| PAL_GLEAN10006158| PANDA_019254| SJS2| soluble differentiation-stimulating factor receptor| STWS| TREES_T100020846| UY3_12599| Y1Q_020271| Z169_13319| lifr

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

Contact

  • Support

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • About Us
  • Login
  • Analyze My Genes
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2019 All Rights Reserved