Summary of KRT14

The gene codes for a protein, keratin 14. Mutations are linked to epidermolysis bullosa simplex [R].


Function

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

Protein names

Recommended name:

Keratin, type I cytoskeletal 14

Short name:

K14

Alternative name(s):

Cytokeratin-14
CK-14
Keratin-14

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Top Gene-Substance Interactions

KRT14 Interacts with These Diseases

Substances That Increase KRT14

Substances That Decrease KRT14

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical