Summary of IGFBP1

The gene codes for a protein, insulin like growth factor binding protein 1. It binds with IGFs [R].

The Function of IGFBP1

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.

Protein names

Recommended name:

Insulin-like growth factor-binding protein 1

Short name:


Alternative name(s):

IGF-binding protein 1
Placental protein 12

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Top Gene-Substance Interactions

IGFBP1 Interacts with These Diseases

Substances That Increase IGFBP1

Substances That Decrease IGFBP1

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity