The Function of HTR6

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling (PubMed:23027611).

Protein names

Recommended name:

5-hydroxytryptamine receptor 6

Short name:

5-HT6

Alternative name(s):

5-HT-6
Serotonin receptor 6

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Top Gene-Substance Interactions

HTR6 Interacts with These Diseases

Substances That Increase HTR6

Substances That Decrease HTR6

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical