Function

Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.

Protein names

Recommended name:

15-hydroxyprostaglandin dehydrogenase [NAD

Short name:

+

Alternative name(s):

15-PGDH
Prostaglandin dehydrogenase 1
Short chain dehydrogenase/reductase family 36C member 1

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Top Gene-Substance Interactions

HPGD Interacts with These Diseases

Substances That Increase HPGD

Substances That Decrease HPGD

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical