Summary

This gene encodes an enzyme that catalyzes the rate limiting step in cholesterol biosynthesis (R). 


Function

Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Protein names

Recommended name:

3-hydroxy-3-methylglutaryl-coenzyme A reductase

Alternative name(s):

HMG-CoA reductase

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