This gene encodes an enzyme that catalyzes the rate limiting step in cholesterol biosynthesis (R). 


Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Protein names

Recommended name:

3-hydroxy-3-methylglutaryl-coenzyme A reductase

Alternative name(s):

HMG-CoA reductase

Get a Grip on Your Health. Use SelfDecode to Interpret your Genome Today! GET INSTANT ACCESS

Top Gene-Substance Interactions

Gene Interacts with Diseases

All Ways to Increase Gene

All Ways to Decrease Gene

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity