Summary of HFE

This gene encodes a protein that helps keep track of the amount of iron in the body. It is associated with anemia (R).

The Function of HFE

Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.

Protein names

Recommended name:

Hereditary hemochromatosis protein

Short name:


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Top Gene-Substance Interactions

HFE Interacts with These Diseases

Substances That Increase HFE

Substances That Decrease HFE

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity