Summary of HDC

HDC (histidine decarboxylase) helps convert L-histidine to histidine. Histidine is important for regulating many processes: neurotransmission, inflammation, smooth muscle tone, and gastric acid secretion (R).

Loss of function of this gene can cause heart failure (R).

The Function of HDC

Catalyzes the biosynthesis of histamine from histidine.

Protein names

Recommended name:

Headcase protein homolog

Alternative name(s):


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Top Gene-Substance Interactions

HDC Interacts with These Diseases

Substances That Increase HDC

Substances That Decrease HDC

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity