Summary of GSTT1

GSTT1 is a theta class glutathione S-transferase. This enzyme has been claimed to have an important role in human carcinogenesis.


Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.

Protein names

Recommended name:

Glutathione S-transferase theta-1

Alternative name(s):

GST class-theta-1
Glutathione transferase T1-1

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Top Gene-Substance Interactions

GSTT1 Interacts with These Diseases

Substances That Increase GSTT1

Substances That Decrease GSTT1

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical