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GREB1 (Growth regulation by estrogen in breast cancer 1)

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The Function of GREB1

May play a role in estrogen-stimulated cell proliferation. Acts as a regulator of hormone-dependent cancer growth in breast and prostate cancers.

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Protein names

Recommended name:

Protein GREB1

Alternative name(s):

Gene regulated in breast cancer 1 protein

GREB1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS13394619 (GREB1) ??
  2. RS1435547 (GREB1) ??
  3. RS73175262 (GREB1) ??

Top Gene-Substance Interactions

GREB1 Interacts with These Diseases

Disease Score

Substances That Increase GREB1

Substances Interaction Organism Category

Substances That Decrease GREB1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • ER-alpha
  • c-Jun
  • Pbx1a
  • Sox9
  • GR-alpha
  • MEF-2A

Tissue specificity:

Expressed in proliferating prostatic tissue and prostate cancer.

Induction:

Estrogen-responsive; regulated by estrogen receptors. Regulated by androgens. The regulatory region of the gene contains 3 estrogen-responsive elements.

*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| 9130004E13| AF180470| AS27_15662| AS28_03578| CB1_001616093| D623_10020805| gene regulated by estrogen in breast cancer| gene regulated by estrogen in breast cancer protein| gene regulated in breast cancer 1 protein| GREB1L| growth regulation by estrogen in breast cancer-like| GW7_14355| H920_07388| I79_007627| M959_05617| MDA_GLEAN10012569| N300_15326| N301_06667| N302_01883| N303_09041| N305_01606| N307_04029| N308_15776| N309_09567| N310_02045| N311_09275| N312_11601| N320_12788| N321_02535| N322_04038| N324_01285| N325_03383| N326_02105| N327_13287| N328_01663| N329_00673| N330_01479| N331_11605| N332_06222| N333_05661| N335_08532| N336_02208| N339_03771| N341_07748| PAL_GLEAN10020139| PANDA_011800| Protein GREB1| protein GREB1-like| RGD1564091| TREES_T100010433| UY3_10339| Y1Q_007228| Y956_15360| Z169_02368| greb1

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