The Function of GABRA1

Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.

Protein names

Recommended name:

Gamma-aminobutyric acid receptor subunit alpha-1

Short name:


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Top Gene-Substance Interactions

GABRA1 Interacts with These Diseases

Substances That Increase GABRA1

Substances That Decrease GABRA1

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity