The Function of GABBR1

Isoform 1E may regulate the formation of functional GABBR1/GABBR2 heterodimers by competing for GABBR2 binding. This could explain the observation that certain small molecule ligands exhibit differential affinity for central versus peripheral sites.

Protein names

Recommended name:

Gamma-aminobutyric acid type B receptor subunit 1

Alternative name(s):

GABA-B receptor 1

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Top Gene-Substance Interactions

GABBR1 Interacts with These Diseases

Substances That Increase GABBR1

Substances That Decrease GABBR1

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity