Summary

The gene codes for fibronectin which is involved in cell adhesion and migration processes. It is important for wound healing and blood coagulation [R].


Function

Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

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