Summary of FN1

The gene codes for fibronectin which is involved in cell adhesion and migration processes. It is important for wound healing and blood coagulation [R].


The Function of FN1

Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Protein names

Recommended name:

Fibronectin

Short name:

FN

Alternative name(s):

Cold-insoluble globulin
CIG

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Top Gene-Substance Interactions

FN1 Interacts with These Diseases

Substances That Increase FN1

Substances That Decrease FN1

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical