Summary of FGF21

FGF21 is a protein that increases metabolism, energy, fat utilization and glucose metabolism.

It's an important mechanism underlying the healthful effects of ketogenesis.

The Function of FGF21

Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.

Protein names

Recommended name:

Fibroblast growth factor 21

Short name:


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Top Gene-Substance Interactions

FGF21 Interacts with These Diseases

Substances That Increase FGF21

Substances That Decrease FGF21

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity