Summary of FECH

This gene encodes a protein that helps make heme, an important component of blood. Mutations can cause problems with blood cells and lead to liver damage (R).


The Function of FECH

Catalyzes the ferrous insertion into protoporphyrin IX.

Protein names

Recommended name:

Ferrochelatase, mitochondrial

Alternative name(s):

Heme synthase
Protoheme ferro-lyase

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Top Gene-Substance Interactions

FECH Interacts with These Diseases

Substances That Increase FECH

Substances That Decrease FECH

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical